Metfendrazin

Metfendrazin
(IUPAC) ime
	1-metil-1-(1-metil-2-fenil-etil)hidrazin
Klinički podaci
Identifikatori
CAS broj	3734-26-7
ATC kod	nije dodeljen
PubChem	19516
ChemSpider	18390
Hemijski podaci
Formula	C10H16N2
Mol. masa	164,25 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C10H16N2/c1-9(12(2)11)8-10-6-4-3-5-7-10/h3-7,9H,8,11H2,1-2H3; Key: MCBDVQRENMFNSU-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	Nije kontrolisana supstanca
Način primene	Oralno

Metfendrazin (HM-11, MO-482, metfendrazin) ireverzibilni i neselektivni je inhibitor monoaminske oksidaze (MAOI) iz hidrazinske hemijske klase.^[4]^[5] On je ispitivan kao potencijalni antidepresiv, ali nije dospeo na tržište.

Reference[uredi - уреди | uredi izvor]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3. edit
↑ Miquel, J., Mijan, C. D. (1962). "Metfendrazine, a new inhibitor of monoamine oxidase". Arch. Inst. Farmacol. Exp. (Madrid) 14: 47–59.
↑ Kothari NJ, Saunders JC, Kline NS, Griffen JA (October 1960). "A comparison of perphenazine, proketazine, nialamide and MO-482 in chronic schizophrenics". The American Journal of Psychiatry 117: 358–60. PMID 13753478. http://ajp.psychiatryonline.org/cgi/pmidlookup?view=long&pmid=13753478.

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