MK-212

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MK-212
MK-212.svg
IUPAC ime
Drugi nazivi CPP
Identifikacija
CAS registarski broj 64022-27-1 YesY
PubChem[1][2] 107992
ChemSpider[3] 97104
Jmol-3D slike Slika 1
Svojstva
Molekulska formula C8H11ClN4
Molarna masa 198.65 g mol−1



Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

MK-212 (CPP, 6-hloro-2-(l-piperazinil)pirazin)[4] je serotoninski agonist.[5] On promoviše sekreciju serumskog prolaktina i kortizola kod ljudi.[6]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Clineschidmt, BV (1979). "MK-212: A serotonin-like agonist in the CNS". General pharmacology 10 (4): 287–90. PMID 488663. 
  5. Bastani, B.; Nash, J. F.; Meltzer, H. Y. (1990). "Prolactin and Cortisol Responses to MK-212, a Serotonin Agonist, in Obsessive-Compulsive Disorder". Archives of General Psychiatry 47 (9): 833–9. doi:10.1001/archpsyc.1990.01810210041006. PMID 2203327. 
  6. Lowy, Martin T.; Meltzer, Herbert Y. (1988). "Stimulation of serum cortisol and prolactin secretion in humans by MK-212, a centrally active serotonin agonist". Biological Psychiatry 23 (8): 818–28. doi:10.1016/0006-3223(88)90070-4. PMID 3365458. 

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