5-Benziloksitriptamin

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5-Benziloksitriptamin
(IUPAC) ime
2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
Klinički podaci
Identifikatori
CAS broj 20776-45-8
ATC kod  ?
PubChem[1][2] 89576
ChemSpider[3] 80845
Hemijski podaci
Formula C17H18N2O 
Mol. masa 266.34 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

5-Benziloksitriptamin (5-BT) je derivat triptamina koji deluje kao agonist 5-HT1D, 5-HT2 i 5-HT6 serotoninskih receptora.[4][5][6][7]

Vidi još[uredi - уреди | uredi izvor]

Literatura[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). "Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens". European Journal of Pharmacology 145 (3): 291–7. PMID 3350047. doi:10.1016/0014-2999(88)90432-3. 
  5. Peroutka SJ, McCarthy BG, Guan XM (1991). "5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent". Life Sciences 49 (6): 409–18. PMID 1650872. doi:10.1016/0024-3205(91)90582-V. 
  6. Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). "Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins". European Journal of Pharmacology 211 (1): 43–6. PMID 1319907. doi:10.1016/0014-2999(92)90260-B. 
  7. Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). "Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells". Neuropharmacology 36 (4-5): 713–20. PMID 9225298. doi:10.1016/S0028-3908(97)00019-1.