Lu AE58054
| |||
| (IUPAC) ime | |||
|---|---|---|---|
| 2-(6-fluoro-1H-indol-3-il)-N-(3-(2,2,3,3,3-pentafluoropropoksi)benzil)etanamin | |||
| Klinički podaci | |||
| Identifikatori | |||
| CAS broj | 467459-31-0 | ||
| ATC kod | nije dodeljen | ||
| PubChem[1][2] | 71587742 | ||
| Hemijski podaci | |||
| Formula | C20H19F5N2O | ||
| Mol. masa | 398,37 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Sinonimi | Lu-AE-58054 | ||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Lu AE58054 je potentan i selektivan antagonist 5-HT6 receptora. On je u razvoju kao augmentaciona terapija za tretman kognitivnih deficita vezanih za Alchajmerovu bolest i šizofreniju.[3][4][4]
References[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ „U.S. Development Programs. - Lundbeck”.
- ↑ 4,0 4,1 „Search of: Lu AE58054 - List Results - ClinicalTrials.gov”.
Spoljašnje veze[uredi | uredi kod]
- Lundbeck expands its pipeline - initiating phase II clinical trials with a new compound for the treatment of schizophrenia Arhivirano 2011-07-09 na Wayback Machine-u
- Lundbeck initiates clinical phase II trials with Lu AE58054 as augmentation treatment in Alzheimer's disease Arhivirano 2010-02-04 na Wayback Machine-u
2-Methil-5-HT • 4-Acetoksi-DET • 4-Acetoksi-DIPT • 4-Acetoksi-DMT • 4-HO-αMT • 4-HO-DIPT • 4-HO-MET • 4-MeO-DMT • 4-Metil-αET • 4-Metil-i • 5-Benziloksitriptamin • 5-Bromo-DMT • 5-Karboksamidotriptamin • 5-Etoksi-αMT • 5-Fluoro-αMT • 5-HO-αMT • 5-HTP • 5-Etoksi-DMT • 5-Etil-DMT • 5-Fluoro-DMT • 5-Metil-DMT • 5-Metoksitriptamin • 5-MeO-7,N,N-TMT • 5-Metil-αET • 5-MeO-αET • 5-MeO-αMT • 5-MeO-DALT • 5-MeO-DET • 5-MeO-DIPT • 5-MeO-DMT • 5-MeO-DPT • 5-MeO-MALT • 5-MeO-MIPT • 5,7-Dihidroksitriptamin • 5-(Noniloksi)triptamin • 6-Fluoro-αMT • 7-Methyl-αET • 7-Metil-DMT • αET • αMT • Aeruginascin • AL-37350A • BW-723C86 • Baeocistin • Bufotenidin • Bufotenin • DALT • Desformilflustrabromin • DET • DiPT • DMT • DPT • Etocibin • EiPT • EMDT • EPT • Etocin • FGIN-127 • FGIN-143 • Ibogain • Indorenat • Iprocin • MET • MiPT • Miprocin • Melatonin • MS-245 • NAS • NMT • Norbaeocistin • Normelatonin • Oksipertin • PiPT • Psilocin • Psilocibin • Rizatriptan • Serotonin • Sumatriptan • Triptamin • Triptofan • Johimbin • Juremamin • Zolmitriptan |