Mebanazin

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Mebanazin
(IUPAC) ime
1-feniletilhidrazin
Klinički podaci
Identifikatori
CAS broj 65-64-5
ATC kod nije dodeljen
PubChem[1][2] 6179
ChemSpider[3] 5944
UNII Z5R55CJ4CG YesY
ChEMBL[4] CHEMBL1909283
Hemijski podaci
Formula C8H12N2 
Mol. masa 136,19 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status Prescription only
Način primene Oralno

Mebanazin (Actomol) je inhibitor monoaminske oksidaze (MAOI) iz hidrazinske hemijske klase, koji je ranije korišten kao antidepresiv tokom 1960-tih, ali je njegova primena prekinuta.[5][6][7]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  5. Gilmour SJ (September 1965). "Clinical trial of mebanazine--a new monoamine oxidase inhibitor". The British Journal of Psychiatry : the Journal of Mental Science 111 (478): 899–902. PMID 5889715. 
  6. Barker JC, Jan IA, Enoch MD (November 1965). "A controlled trial of mebanazine ('Actomol') in depression". The British Journal of Psychiatry : the Journal of Mental Science 111 (480): 1095–100. PMID 5320546. 
  7. Knott F (1965). "A preliminary trial of mebanazine in depressive states". The Journal of New Drugs 5 (6): 345–7. PMID 5327282. 

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