Bitolterol

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Bitolterol
(IUPAC) ime
(RS)-[4-(1-Hidroksi-2-tert-butilamino-etil)- 2-(4-metilbenzoil)oksi-fenil] 4-metilbenzoat
Klinički podaci
AHFS/Drugs.com Mikromedeks, detaljne potrošačke informacije
MedlinePlus a601236
Identifikatori
CAS broj 30392-41-7
ATC kod R03AC17
PubChem[1][2] 35330
DrugBank DB00901
ChemSpider[3] 32525
UNII 9KY0QXD6LI YesY
ChEMBL[4] CHEMBL1201295 YesY
Hemijski podaci
Formula C28H31NO5 
Mol. masa 461,549 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Bitolterol mesilat (Tornalat) je agonist β2-adrenergičkog receptora koji se koristi za olakšavanje bronhospazama kod oboljenja kao što su astma i hronična opstruktivna bolest pluća.[5]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Friedel HA, Brogden RN (1988). „Bitolterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible obstructive airways disease”. Drugs 35: 22-41. http://ukpmc.ac.uk/abstract/MED/3278878/reload=0;jsessionid=c0HU7QxJoemJjpllzd68.24. 

Spoljašnje veze[uredi - уреди | uredi izvor]


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