Karazolol

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Karazolol
(IUPAC) ime
1-(9H-karbazol-4-iloksi)-3-(propan-2-ilamino)propan-2-ol
Klinički podaci
AHFS/Drugs.com Internacionalno ime leka
Identifikatori
CAS broj 57775-29-8
ATCvet kod QC07AA90
PubChem[1][2] 71739
ChemSpider[3] 64783
UNII 29PW75S82A YesY
Hemijski podaci
Formula C18H22N2O2 
Mol. masa 298,38
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Karazolol je antagonist/parcijalni inverzni agonist visokog afiniteta (beta blokator) β-adrenergičkog receptora.[4]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Innis RB, Corrēa FM, Synder SH (1979). "Carazolol, an extremely potent beta-adrenergic blocker: binding to beta-receptors in brain membranes". Life Sci. 24 (24): 2255–64. PMID 41147. doi:10.1016/0024-3205(79)90102-4. 

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