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Tropolon

Izvor: Wikipedija
Tropolon[1]
Skeletal formula of tropolone
Skeletal formula of tropolone
Space-filling model of tropolone
Space-filling model of tropolone
IUPAC ime
Drugi nazivi 2-Hidroksitropon; Purpurokatehol
Identifikacija
CAS registarski broj 533-75-5 DaY
PubChem[2][3] 10789
UNII 7L6DL16P1T DaY
ChEMBL[4] CHEMBL121188 DaY
Jmol-3D slike Slika 1
Svojstva
Molekulska formula C7H6O2
Molarna masa 122.12 g/mol
Tačka topljenja

50–52 °C

Tačka ključanja

80–84 °C (0.1 mmHg)

pKa 6.89
Baznost (pKb) -0.5
Opasnost
S-oznake S22 S24/25
Tačka paljenja 112 °C
Srodna jedinjenja
Srodna jedinjenja Hinokitiol (4-izopropil-tropolon)

 DaY (šta je ovo?)   (verifikuj)

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

Tropolon je derivat tropona sa hidroksilnom grupom u 2-poziciji.

Dva moguća metoda za sintezu tropolona su:

Sinteza tropolona
Sinteza tropolona

Ovaj molekul je inhibitor groždane polifenolne oksidaze.[5][6]

Reference

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  1. Tropolone at Sigma-Aldrich
  2. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  3. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Time-dependent inhibition of grape polyphenol oxidase by tropolone. Edelmira Valero, Manuela Garcia-Moreno, Ramon Varon and Francisco Garcia-Carmona, J. Agric. Food Chem., 1991, 39 (6), pp 1043–1046, DOI:10.1021/jf00006a007
  6. Chedgy, Russell. Secondary metabolites of Western red cedar (Thuja plicata): their biotechnological applications and role in conferring natural durability. LAP Lambert Academic Publishing, 2010, ISBN 3838346610, ISBN 978-3838346618

Spoljašnje veze

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