Trimazosin

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Trimazosin
(IUPAC) ime
(2-hidroksi-2-metilpropil) 4-(4-amino-6,7,8-trimetoksihinazolin-2-il)piperazin-1-karboksilat
Klinički podaci
Identifikatori
CAS broj 53746-46-6
ATC kod C02CA03
PubChem[1][2] 37264
UNII 31L760807H YesY
ChEMBL[3] CHEMBL513301 YesY
Hemijski podaci
Formula C20H29N5O6 
Mol. masa 435,47 g/mol
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

Trimazosin je simpatomimetički lek. On je alfa blokator.[4]

Završni stupanj sinteze trimazosina je[5]

Trimazocin.png

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  4. van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. PMID 3780829. doi:10.1007/BF00870988. 
  5. Hess, H. J.; 1972, U.S. Patent 3.669.968

Spoljašnje veze[uredi - уреди | uredi izvor]


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