Izoksuprin

Izoksuprin
	4-{1-hidroksi-2-[(1-metil-2-fenoksietil)amino]propil}fenol
Drugi nazivi	Vasodilian, Duvadilan
Identifikacija
CAS registarski broj	395-28-8
PubChem	3783
ChemSpider	3651
KEGG	D08092
MeSH	Isoxsuprine
ChEMBL	CHEMBL1197051
ATC code	C04AA01
Jmol-3D slike	Slika 1
SMILES
	O(c1ccccc1)CC(NC(C)C(O)c2ccc(O)cc2)C
InChI
	InChI=1S/C18H23NO3/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15/h3-11,13-14,18-21H,12H2,1-2H3 ; Kod: BMUKKTUHUDJSNZ-UHFFFAOYSA-N InChI=1/C18H23NO3/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15/h3-11,13-14,18-21H,12H2,1-2H3; Kod: BMUKKTUHUDJSNZ-UHFFFAOYAW
Svojstva
Molekulska formula	C18H23NO3
Molarna masa	301.38 g mol−1
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Izoksuprin (Izoksuprin hidrohlorid, Vasodilan) je lek koji se koristi kao vazodilatator^[7] kod ljudi. Izoksuprin je beta-adrenergički agonist koji uzrokuje direktnu relaksaciju materičnih i vaskularnih glatkih mišića putem beta-2 receptora.^[8]

Reference[uredi - уреди | uredi izvor]

↑ Isoxsuprine - Compound Summary, PubChem.
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0061%28200004%2917:1%3C48::AID-YEA2%3E3.0.CO;2-H/full.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Gozo EG, Yebes RB (November 1984). „Hemodynamic effects of isoxsuprine in cardiac failure”. Chest 86 (5): 736–40. DOI:10.1378/chest.86.5.736. PMID 6488912. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=6488912.
↑ Falkay, G.; Kovács, L. (1986). „Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors”. Journal of perinatal medicine 14 (2): 109–113. PMID 2874205.

Literatura[uredi - уреди | uredi izvor]

Forney, Barbara C, MS, VMD. Equine Medications, Revised Edition. Blood Horse Publications. Lexington, KY. Copyright 2007.

Spoljašnje veze[uredi - уреди | uredi izvor]

[1] Isoxsuprine - Compound Summary, PubChem.

[2] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737. edit

[3] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[4] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3. edit

[5] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0061%28200004%2917:1%3C48::AID-YEA2%3E3.0.CO;2-H/full.

[6] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[pmid6488912-7] Gozo EG, Yebes RB (November 1984). „Hemodynamic effects of isoxsuprine in cardiac failure”. Chest 86 (5): 736–40. DOI:10.1378/chest.86.5.736. PMID 6488912. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=6488912.

[8] Falkay, G.; Kovács, L. (1986). „Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors”. Journal of perinatal medicine 14 (2): 109–113. PMID 2874205.

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Izoksuprin

Reference[uredi - уреди | uredi izvor]

Literatura[uredi - уреди | uredi izvor]

Spoljašnje veze[uredi - уреди | uredi izvor]

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