Diacetolol

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Diacetolol
(IUPAC) ime
N-[3-acetil-4-[2-hidroksi-3-(izopropilamino)propoksi]fenil]acetamid
Klinički podaci
Identifikatori
CAS broj 22568-64-5
ATC kod nije dodeljen
PubChem[1][2] 50894
ChemSpider[3] 46139
UNII 4ER0CZ5G7C YesY
Hemijski podaci
Formula C16H24N2O4 
Mol. masa 308,37 g/mol
SMILES eMolekuli & PubHem
Farmakokinetički podaci
Poluvreme eliminacije 8-13 sati
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status Prescription only
Način primene Oralno

Diacetolol je primarni metabolit acebutolola. On je beta blokator i anti-aritmički agens.[4]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Berkeley Basil, Roy Jordan (1982-05-07). "Pharmacological properties of diacetolol (M&B 16,942), a major metabolite of acebutolol". European Journal of Pharmacology 80: 47–56. 

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