Dapiprazol

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Dapiprazol
(IUPAC) ime
32-[4-(2-metilfenil)piperazin-1-il]etil5,6,7,8-
tetrahidro-[1,2,4]triazolo[4,5-a]piridin
Klinički podaci
AHFS/Drugs.com Potrošačka informacije o leku
MedlinePlus a601043
Identifikatori
CAS broj 72822-12-9
ATC kod S01EX02
PubChem[1][2] 3033538
DrugBank DB00298
ChemSpider[3] 2298190
UNII 5RNZ8GJO7K YesY
KEGG[4] D07775 YesY
ChEBI CHEBI:51066 YesY
ChEMBL[5] CHEMBL1201216 YesY
Hemijski podaci
Formula C19H27N5 
Mol. masa 325,451 g/mol
SMILES eMolekuli & PubHem
Farmakokinetički podaci
Bioraspoloživost Zanemarljiva pri topičkom doziranju
Farmakoinformacioni podaci
Trudnoća ?
Pravni status Prescription only
Način primene Topikalno (kapi za oči)

Dapiprazol (Rev-Eyes) je alfa blokator. On se koristi za oporavak od midrijaze nakon pregleda očiju.[6]

Reference[uredi - уреди | uredi kôd]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0061%28200004%2917:1%3C48::AID-YEA2%3E3.0.CO;2-H/full. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  6. Doughty, Michael J.; Lyle, William M. (May 1992). „A Review of the Clinical Pharmacokinetics of Pilocarpine, Moxisylyte (Thymoxamine), and Dapiprazole in the Reversal of Diagnostic Pupillary Dilation”. Optometry & Vision Science 69 (5). http://journals.lww.com/optvissci/Abstract/1992/05000/A_Review_of_the_Clinical_Pharmacokinetics_of.5.aspx. 

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