Niguldipin
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Niguldipin | |||
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IUPAC ime |
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Identifikacija | |||
CAS registarski broj | 102993-22-6 | ||
PubChem[1][2] | 1236 | ||
ChemSpider[3] | 1199 | ||
ChEMBL[4] | CHEMBL41929 | ||
Jmol-3D slike | Slika 1 | ||
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Svojstva | |||
Molekulska formula | C36H39N3O6 | ||
Molarna masa | 609,71136 | ||
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala | |||
Infobox references |
Niguldipin je blokator kalcijumovog kanala i antagonist a1-adrenergičkog receptora.[5]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Boer R, Grassegger A, Schudt C, Glossmann H (May 1989). „(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors”. European Journal of Pharmacology 172 (2): 131–45. DOI:10.1016/0922-4106(89)90004-7. PMID 2548881.