Befunolol

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Befunolol
(IUPAC) ime
(RS)-17-[2-hidroksi-3-(propan-2-ilamino)propoksi]- 1-benzofuran-2-il}etanon
Klinički podaci
Robne marke Benfuran, Bentos, Betaclar, Glauconex
AHFS/Drugs.com Internacionalno ime leka
Identifikatori
CAS broj 39552-01-7
ATC kod S01ED06
PubChem[1][2] 2309
ChemSpider[3] 2219
UNII 418546MT3A YesY
KEGG[4] D07496 YesY
ChEMBL[5] CHEMBL153984 YesY
Hemijski podaci
Formula C16H21NO4 
Mol. masa 291,342 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Befunolol je beta blokator sa intrinsičnom simpatomimetičkom aktivnošću koji se koristi u tretmanu glaukoma.[6]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  6. Stephan Reichl, Christel C Müller-Goymann (2003-02-01). "The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride". International Journal of Pharmaceutics 250 (1): 191–201. 

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