3,4-Dihidroksistiren

Iz Wikipedije, slobodne enciklopedije
Idi na navigaciju Idi na pretragu
3,4-Dihidroksistiren
(IUPAC) ime
4-vinilbenzen-1,2-diol
Klinički podaci
Identifikatori
CAS broj 6053-02-7
ATC kod nije dodeljen
PubChem[1][2] 151398
ChemSpider[3] 133430
KEGG[4] C06224 YesY
Hemijski podaci
Formula C8H8O2 
Mol. masa 136,15 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status Nije kontrolisana supstanca

3,4-Dihidroksistiren (DHS) je centralno delujući inhibitor enzima fenilalaninska hidroksilaza (PH).[5] DHS i drugi PH inhibitori verovatno neće ući u kliničku upotrebu zbog njihove sposobnosti da indukuju hiperfenilalaninemiju i fenilketonuriju.

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0061%28200004%2917:1%3C48::AID-YEA2%3E3.0.CO;2-H/full. 
  5. Koizumi S, Matsushima Y, Nagatsu T, Iinuma H, Takeuchi T, Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica Et Biophysica Acta 789 (2): 111–8. DOI:10.1016/0167-4838(84)90194-8. PMID 6148105. http://linkinghub.elsevier.com/retrieve/pii/0167-4838(84)90194-8. 

Vidi još[uredi - уреди | uredi izvor]