2-OH-NPA

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2-OH-NPA
(IUPAC) ime
(R)-2,10,11-trihidroksi-N-propilnoraporfin
Klinički podaci
Identifikatori
CAS broj 79640-85-0
ATC kod  ?
PubChem[1][2] 6603798
ChemSpider[3] 8244599
Hemijski podaci
Formula C19H21NO3 
Mol. masa 311,374 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

2-OH-NPA je lek koji se koristi u naučnim istraživanjima i koji deluje kao potentan i selektivan agonist za dopaminski D2 receptor.[4]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Gao YG, Baldessarini RJ, Kula NS, Neumeyer JL (1990). "Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues". Journal of medicinal chemistry 33 (6): 1800–5. PMID 1971309. doi:10.1021/jm00168a040.