Etikloprid

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Etikloprid
(IUPAC) ime
3-hloro-5-etil-N[(2S)-1-etilpirolidin-2-il] metil6-hidroksi-2-metoksibenzamid
Klinički podaci
Identifikatori
CAS broj 97612-24-3
ATC kod nije dodeljen
PubChem[1][2] 57267
UNII J8M468HBH4 YesY
ChEMBL[3] CHEMBL8946 YesY
Hemijski podaci
Formula C17H25ClN2O3 
Mol. masa 340,845 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Etikloprid je selektivni dopaminski antagonist koji deluje na dopaminski receptor D2. On se prvenstveno koristi u farmakološkim istraživanjima.[4][5]

Reference[uredi - уреди | uredi kôd]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  4. „Eticlopride hydrochloride”. http://www.abcam.com/Eticlopride-hydrochloride-ab120602.html. 
  5. Renee Claytora, Joshua A. Lilea, 1, Michael A. Nader (2006). „The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys”. Pharmacology Biochemistry and Behavior 83 (3): 456–464. http://www.sciencedirect.com/science/article/pii/S0091305706000669. 

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