Hineloran

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Hineloran
(IUPAC) ime
(5aR,9aR)-6-propil-5a,7,8,9,9a,10-heksahidro-5H-pirido[2,3-g]hinazolin-2-amin
Klinički podaci
Identifikatori
CAS broj 97548-97-5
ATC kod nije dodeljen
PubChem[1][2] 57242
UNII Z0X4VT3Y1Q DaY
KEGG[3] D05677 DaY
ChEMBL[4] CHEMBL155731 DaY
Hemijski podaci
Formula C14H22N4 
Mol. masa 246,350 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Hineloran je leki koji deluje kao selektivni dopaminski agonist za D2 podtipe.[5][6][7]

Reference[uredi | uredi kod]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Caine SB, Negus SS, Mello NK, Patel S, Bristow L, Kulagowski J, Vallone D, Saiardi A, Borrelli E (April 2002). „Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists”. Journal of Neuroscience 22 (7): 2977–88. PMID 11923462. 
  6. Gasior M, Paronis CA, Bergman J (January 2004). „Modification by dopaminergic drugs of choice behavior under concurrent schedules of intravenous saline and food delivery in monkeys”. The Journal of Pharmacology and Experimental Therapeutics 308 (1): 249–59. DOI:10.1124/jpet.103.052795. PMID 14563783. 
  7. Brooks JM, Sarter M, Bruno JP (September 2007). „D2-like receptors in nucleus accumbens negatively modulate acetylcholine release in prefrontal cortex”. Neuropharmacology 53 (3): 455–63. DOI:10.1016/j.neuropharm.2007.06.006. PMC 2000917. PMID 17681559. 

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