Tertatolol

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Tertatolol
(IUPAC) ime
(±)-1-(tert-butilamino)-3-(3,4-dihidro-2H-tiohromen-8-iloksi)propan-2-ol
Klinički podaci
AHFS/Drugs.com Internacionalno ime leka
Identifikatori
CAS broj 34784-64-0
ATC kod C07AA16
PubChem[1][2] 36920
UNII 9ZO341YQXP YesY
KEGG[3] D07182 YesY
ChEMBL[4] CHEMBL434200 YesY
Hemijski podaci
Formula C16H25NO2S 
Mol. masa 295,44 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status Prescription only
Način primene Oralno

Tertatolol (Artex, Artexal, Prenalex) je lek u klasi beta blokatora. On se koristi za tretiranje visokog krvnog pritiska. Tertatolol je otkrila francuska farmaceutska kompanija Servijer i u prodaji je u Evropi.[5]

Tertatolol deluje kao antagonist 5-HT1A receptor, slično pindololu.[6][7]

Vidi još[uredi - уреди | uredi izvor]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  5. Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0. http://books.google.com/books?id=5GpcTQD_L2oC&lpg=PA1002&pg=PA1002#v=onepage&q=&f=false. 
  6. Jolas T, Haj-Dahmane S, Lanfumey L et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology 347 (5): 453–63. PMID 7686633. 
  7. Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8. http://books.google.com/books?id=lfo0hGqIex0C&lpg=PA37&pg=PA37#v=onepage&q=&f=false. 

Literatura[uredi - уреди | uredi izvor]

Spoljašnje veze[uredi - уреди | uredi izvor]


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