Butofilolol

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Butofilolol
(IUPAC) ime
(RS)-1-[2-[3-(tert-butilamino)-2-hidroksipropoksi]-5-fluorofenil]butan-1-on
Klinički podaci
Identifikatori
CAS broj 64552-17-6
ATC kod nije dodeljen
PubChem[1][2] 68838
ChemSpider[3] 62071
UNII 4AZC6Y5A8G YesY
ChEMBL[4] CHEMBL157443 YesY
Hemijski podaci
Formula C17H26FNO3 
Mol. masa 311,392 g/mol
SMILES eMolekuli & PubHem
Sinonimi CM-6805
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Butofilolol (Cafide) je beta-blokator koji potencijalno može naći primenu u tretmanu primarne hipertenzije (visokog krvnog pritiska).[5][6] Ovaj lek nije plasiran na tržište.

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  5. Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International journal of clinical pharmacology research 4 (3): 175–83. PMID 6149195. 
  6. Toussain, P; Gay, G; Debry, G (1983). "Long-term hypotensive treatment by butofilolol". Annales de cardiologie et d'angeiologie 32 (4): 277–83. PMID 6412614. 

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