Abanohil
Izgled
(IUPAC) ime | |
---|---|
2-(6,7-dimetoksi-3,4-dihidro-1H-izohinolin-2-il)-6,7-dimetoksihinolin-4-amin | |
Klinički podaci | |
Identifikatori | |
CAS broj | 90402-40-7 |
ATC kod | nije dodeljen |
PubChem[1][2] | 164089 |
ChemSpider[3] | 143896 |
UNII | F738MWY53L |
ChEMBL[4] | CHEMBL324090 |
Hemijski podaci | |
Formula | C22H25N3O4 |
Mol. masa | 395,452 g/mol |
SMILES | eMolekuli & PubHem |
Farmakoinformacioni podaci | |
Trudnoća | ? |
Pravni status |
Abanohil je antagonist α1-adrenergičkog receptora.[5]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Tham, TC; Guy, S; Shanks, RG; Harron, DW (1992). „Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man”. British Journal of Clinical Pharmacology 33 (4): 405–9. PMC 1381330. PMID 1349492.