Vortioksetin

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Vortioksetin
(IUPAC) ime
1-(2-((2,4-dimetilfenil)tio)fenil)piperazin
Klinički podaci
Identifikatori
CAS broj 508233-74-7
ATC kod nije dodeljen
PubChem[1][2] 9966051
ChemSpider[3] 26286009
KEGG[4] D10184 YesY
Hemijski podaci
Formula C18H22N2S 
Mol. masa 298,45 g/mol
SMILES eMolekuli & PubHem
Sinonimi Lu AA21004
Farmakoinformacioni podaci
Trudnoća ?
Pravni status
Način primene Oralno

Vortioksetin (Lu AA21004) je eksperimentalni lek, koji je u razvoju za tretman kliničke depresije i generalizovanog anksioznog poremećaja.[5][6][7].

Reference[uredi - уреди | uredi kôd]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0061%28200004%2917:1%3C48::AID-YEA2%3E3.0.CO;2-H/full. 
  5. Jancin B (December 2009). „Lu AA21004 Looks Promising for Depression”. Clinical Psychiatry News 37 (12): 24–25. DOI:10.1016/S0270-6644(09)70441-2. http://www.clinicalpsychiatrynews.com/article/S0270-6644(09)70441-2/preview. 
  6. „Lundbeck seeks European approval of antidepressant”. Arhivirano iz originala 2013-12-03. https://web.archive.org/web/20131203024050/http://uk.reuters.com/article/2012/09/20/us-lundbeck-vortioxetine-idUKBRE88J09620120920?feedType=RSS&feedName=healthNews. 
  7. „Application filed to the U.S. Food and Drug Administration for approval of its antidepressant, vortioxetine”. Arhivirano iz originala 2013-12-03. https://web.archive.org/web/20131203022412/http://www.reuters.com/article/2012/10/02/markets-nordics-factors-idUSL6E8L20VJ20121002?type=marketsNews. 

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