Eltoprazin

Eltoprazin
(IUPAC) ime
	1-(2,3-dihidro-1,4-benzodioksin-8-il)piperazin
Klinički podaci
Identifikatori
CAS broj	98224-03-4
ATC kod	nije dodeljen
PubChem	65853
ChemSpider	59265
UNII	510M006KO6
ChEMBL	CHEMBL282614
Hemijski podaci
Formula	C12H16N2O2
Mol. masa	220.121 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2 ; Key: WVLHGCRWEHCIOT-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Eltoprazin (DU-28,853) je lek iz fenilpiperazinske klase. On je antiagresivni agens.^[5] Eltoprazin deluje kao agonist na 5-HT_1A i 5-HT_1B receptorima i kao antagonist na 5-HT_2C receptor.^[6] On je blisko srodan sa fluprazinom i batoprazinom, koji imaju slično dejstvo.

Reference[uredi - уреди | uredi izvor]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Olivier B, Mos J, Rasmussen D. (1990). "Behavioural pharmacology of the serenic, eltoprazine". Drug Metabol Drug Interact. 8 (1-2): 31–83. DOI:10.1515/DMDI.1990.8.1-2.31. PMID 2091890.
↑ Schipper J, Tulp MT, Sijbesma H. (1990). "Neurochemical profile of eltoprazine.". Drug Metabol Drug Interact. 8 (1-2): 85–114. PMID 1982626.

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