TAS2R50

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Receptor ukusa tip 2 član 50
Identifikatori
SimboliTAS2R50; T2R50; T2R51; TAS2R51
Vanjski IDOMIM609627 HomoloGene88474 IUPHAR: GeneCards: TAS2R50 Gene
Ortolozi
VrstaČovekMiš
Entrez259296n/a
EnsemblENSG00000212126n/a
UniProtP59544n/a
RefSeq (mRNA)NM_176890.2n/a
RefSeq (protein)NP_795371.2n/a
Lokacija (UCSC)Chr 12:
11.14 - 11.14 Mb
n/a
PubMed pretraga[1]n/a

Receptor ukusa tip 2 član 50 je protein koji je kod ljudi kodiran TAS2R50 genom.[1][2][3][4]

TAS2R50 pripada velikoj familiji TAS2R receptora. TAS2R receptori su izraženi na površini ćelija ukusa i posreduju percepciju gorkog ukusa putem G protein spregnutog puta sekundarnih glasnika (Conte et al., 2002).[4]

Reference[uredi | uredi kod]

  1. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). „The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides”. Nat Genet 32 (3): 397–401. DOI:10.1038/ng1014. PMID 12379855. 
  2. Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). „Identification and characterization of human taste receptor genes belonging to the TAS2R family”. Cytogenet Genome Res 98 (1): 45–53. DOI:10.1159/000068546. PMID 12584440. 
  3. Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP (Sep 2005). „Identification of Four Gene Variants Associated with Myocardial Infarction”. Am J Hum Genet 77 (4): 596–605. DOI:10.1086/491674. PMC 1275608. PMID 16175505. 
  4. 4,0 4,1 „Entrez Gene: TAS2R50 taste receptor, type 2, member 50”. 

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