LPAR5

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Receptor lizofosfatidne kiseline 5
Identifikatori
SimboliLPAR5; GPR92 ; GPR93; KPG_010; LPA5
Vanjski IDOMIM606926 MGI2685918 HomoloGene10696 IUPHAR: GeneCards: LPAR5 Gene
Ortolozi
VrstaČovekMiš
Entrez57121381810
EnsemblENSG00000184574ENSMUSG00000067714
UniProtQ9H1C0n/a
RefSeq (mRNA)NM_020400XM_355812
RefSeq (protein)NP_065133XP_355812
Lokacija (UCSC)Chr 12:
6.6 - 6.62 Mb
Chr 6:
125.03 - 125.05 Mb
PubMed pretraga[1][2]

-{LPA5}-, receptor lizofosfatidne kiseline 5, je protein koji je kod čoveka kodiran -{LPAR5}- gena.[1][2][3][4][5] -{LPA5}- je G protein-spregnuti receptor koji vezuje lipidni signalni molekul lizofosfatidnu kiselinu (-{LPA}-).[6]

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Reference[uredi - уреди | uredi izvor]

  1. Adhr, Consortium; Strom, Tim M.; White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Lorenz-Depiereux, Bettina; Grabowski, Monika; Meitinger, Thomas (Dec 2000). "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23". Nat Genet 26 (3): 345–8. PMID 11062477. doi:10.1038/81664.  Check date values in: |date= (help)
  2. Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83–91. PMID 11574155. doi:10.1016/S0378-1119(01)00651-5.  Check date values in: |date= (help)
  3. Lee CW, Rivera R, Gardell S, Dubin AE, Chun J (Aug 2006). "GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5". J Biol Chem 281 (33): 23589–97. PMID 16774927. doi:10.1074/jbc.M603670200.  Check date values in: |date= (help)
  4. Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B (Jul 2006). "Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes". J Pharmacol Exp Ther 318 (2): 619–28. PMID 16651401. doi:10.1124/jpet.105.098848.  Check date values in: |date= (help)
  5. "Entrez Gene: GPR92 G protein-coupled receptor 92". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57121. 
  6. Choi JW, Herr DR, Noguchi K, Yung YC, Lee C-W, Mutoh T, Lin M-E, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology 50 (1): 157–186. PMID 20055701. doi:10.1146/annurev.pharmtox.010909.105753. 

Literatura[uredi - уреди | uredi izvor]