LPAR5

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Receptor lizofosfatidne kiseline 5
Identifikatori
SimboliLPAR5; GPR92 ; GPR93; KPG_010; LPA5
Vanjski IDOMIM606926 MGI2685918 HomoloGene10696 IUPHAR: GeneCards: LPAR5 Gene
Ortolozi
VrstaČovekMiš
Entrez57121381810
EnsemblENSG00000184574ENSMUSG00000067714
UniProtQ9H1C0n/a
RefSeq (mRNA)NM_020400XM_355812
RefSeq (protein)NP_065133XP_355812
Lokacija (UCSC)Chr 12:
6.6 - 6.62 Mb
Chr 6:
125.03 - 125.05 Mb
PubMed pretraga[1][2]

-{LPA5}-, receptor lizofosfatidne kiseline 5, je protein koji je kod čoveka kodiran -{LPAR5}- gena.[1][2][3][4][5] -{LPA5}- je G protein-spregnuti receptor koji vezuje lipidni signalni molekul lizofosfatidnu kiselinu (-{LPA}-).[6]

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Reference[uredi - уреди | uredi kôd]

  1. Adhr, Consortium; Strom, Tim M.; White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Lorenz-Depiereux, Bettina; Grabowski, Monika i dr.. (Dec 2000). „Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23”. Nat Genet 26 (3): 345–8. DOI:10.1038/81664. PMID 11062477. 
  2. Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene 275 (1): 83–91. DOI:10.1016/S0378-1119(01)00651-5. PMID 11574155. 
  3. Lee CW, Rivera R, Gardell S, Dubin AE, Chun J (Aug 2006). „GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5”. J Biol Chem 281 (33): 23589–97. DOI:10.1074/jbc.M603670200. PMID 16774927. 
  4. Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B (Jul 2006). „Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes”. J Pharmacol Exp Ther 318 (2): 619–28. DOI:10.1124/jpet.105.098848. PMID 16651401. 
  5. „Entrez Gene: GPR92 G protein-coupled receptor 92”. http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57121. 
  6. Choi JW, Herr DR, Noguchi K, Yung YC, Lee C-W, Mutoh T, Lin M-E, Teo ST, Park KE, Mosley AN, Chun J (January 2010). „LPA Receptors: Subtypes and Biological Actions”. Annual Review of Pharmacology and Toxicology 50 (1): 157–186. DOI:10.1146/annurev.pharmtox.010909.105753. PMID 20055701. http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.pharmtox.010909.105753. 

Literatura[uredi - уреди | uredi kôd]