GPR124

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G protein spregnuti receptor 124
Identifikatori
SimboliGPR124; TEM5
Vanjski IDOMIM606823 MGI1925810 HomoloGene13112 IUPHAR: GPR124 GeneCards: GPR124 Gene
Pregled RNK izražavanja
PBB GE GPR124 221814 at tn.png
PBB GE GPR124 65718 at tn.png
podaci
Ortolozi
VrstaČovekMiš
Entrez2596078560
EnsemblENSG00000020181ENSMUSG00000031486
UniProtQ96PE1Q91ZV8
RefSeq (mRNA)NM_032777.9NM_054044.2
RefSeq (protein)NP_116166.9NP_473385.2
Lokacija (UCSC)Chr 8:
37.64 - 37.7 Mb
Chr 8:
28.2 - 28.23 Mb
PubMed pretraga[1][2]

G protein spregnuti receptor 124 je protein koji je kod ljudi kodiran GPR124 genom.[1][2][3]

Interakcije[uredi - уреди | uredi izvor]

GPR124 formira interakcije sa interact sa DLG1.[4]

Reference[uredi - уреди | uredi izvor]

  1. Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (September 2001). "Cell surface tumor endothelial markers are conserved in mice and humans". Cancer Res 61 (18): 6649–55. PMID 11559528. 
  2. Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (February 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochem Biophys Res Commun 301 (3): 725–34. PMID 12565841. doi:10.1016/S0006-291X(03)00026-3. 
  3. "Entrez Gene: GPR124 G protein-coupled receptor 124". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25960. 
  4. Yamamoto, Yasunori; Irie Kenji, Asada Masanori, Mino Akihisa, Mandai Kenji, Takai Yoshimi (May 2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein". Oncogene (England) 23 (22): 3889–97. ISSN 0950-9232. PMID 15021905. doi:10.1038/sj.onc.1207495. 

Literatura[uredi - уреди | uredi izvor]

  • Nakajima D, Okazaki N, Yamakawa H et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954. doi:10.1093/dnares/9.3.99. 
  • Nagase T, Kikuno R, Ishikawa K et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (2): 143–50. PMID 10819331. doi:10.1093/dnares/7.2.143. 
  • Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899. 
  • Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 
  • Yamamoto Y, Irie K, Asada M et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.". Oncogene 23 (22): 3889–97. PMID 15021905. doi:10.1038/sj.onc.1207495. 
  • Bjarnadóttir TK, Fredriksson R, Höglund PJ et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.". Genomics 84 (1): 23–33. PMID 15203201. doi:10.1016/j.ygeno.2003.12.004. 
  • Vallon M, Essler M (2006). "Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans.". J. Biol. Chem. 281 (45): 34179–88. PMID 16982628. doi:10.1074/jbc.M605291200.