PRRP

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Prolaktin-oslobađajući hormonski receptor
Identifikatori
SimboliPRLHR; GPR10; GR3; MGC126539; MGC126541; PrRPR
Vanjski IDOMIM600895 MGI2135956 HomoloGene3134 IUPHAR: PRRP GeneCards: PRLHR Gene
Ortolozi
VrstaČovekMiš
Entrez2834226278
EnsemblENSG00000119973ENSMUSG00000045052
UniProtP49683Q059H6
RefSeq (mRNA)NM_004248NM_201615
RefSeq (protein)NP_004239NP_963909
Lokacija (UCSC)Chr 10:
120.34 - 120.34 Mb
Chr 19:
60.52 - 60.52 Mb
PubMed pretraga[1][2]

PRRP, prolaktin-oslobađajući hormonski receptor, je G-protein spregnuti receptor[1] koji vezuje prolaktin oslobađajući hormon.[2]

PRLHR je 7-transmembranski receptor za prolaktin-oslobađajući hormon (PRLH; MIM 602663). On je visoko izražen u prednjoj hipofizi.[3][4]

Reference[uredi - уреди | uredi izvor]

  1. Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P (1995). "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors". Genomics 29 (2): 335–44. DOI:10.1006/geno.1995.9996. PMID 8666380. 
  2. Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M (1998). "A prolactin-releasing peptide in the brain". Nature 393 (6682): 272–6. DOI:10.1038/30515. PMID 9607765. 
  3. Ozawa A, Yamada M, Satoh T, et al. (April 2002). "Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 Receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region". Molecular Endocrinology (Baltimore, Md.) 16 (4): 785–98. PMID 11923475. http://mend.endojournals.org/cgi/pmidlookup?view=long&pmid=11923475. Pristupljeno 2011-03-28. 
  4. „Entrez Gene: PRLHR prolactin releasing hormone receptor”. http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2834. 

Literatura[uredi - уреди | uredi izvor]

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