Receptor 1 faktora stimulacije kolonija

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Receptor 1 faktora stimulacije kolonija

Prikaz baziran na PDB 2I0V.
Dostupne strukture
2I0V, 2I0Y, 2I1M, 2OGV, 3BEA, 3DPK, 3KRJ, 3KRL, 3LCD, 3LCO, 4DKD, 4HW7
Identifikatori
SimboliCSF1R; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Vanjski IDOMIM164770 MGI1339758 HomoloGene3817 GeneCards: CSF1R Gene
EC broj2.7.10.1
Pregled RNK izražavanja
PBB GE CSF1R 203104 at tn.png
podaci
Ortolozi
VrstaČovekMiš
Entrez143612978
EnsemblENSG00000182578ENSMUSG00000024621
UniProtP07333P09581
Ref. Sekv. (iRNK)NM_001288705NM_001037859
Ref. Sekv. (protein)NP_001275634NP_001032948
Lokacija (UCSC)Chr 5:
149.43 - 149.49 Mb
Chr 18:
61.11 - 61.13 Mb
PubMed pretraga[1][2]

Receptor 1 faktora stimulacije kolonija (CSF1R, receptor faktora stimulacije makrofagnih kolonija, M-CSFR, CD115, Klaster Diferencijacije 115), je protein sa ćelijske površine koji je kod ljudi kodiran CSF1R genom.[1][2] On je receptor za citokin sa imenom faktor stimulacije kolonija 1.

Interakcije[uredi - уреди | uredi izvor]

Ovaj receptor formira interakcije sa:

Vidi još[uredi - уреди | uredi izvor]

Reference[uredi - уреди | uredi izvor]

  1. EntrezGene 1436
  2. Galland F, Stefanova M, Lafage M, Birnbaum D (1992). "Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15→q23". Cytogenet. Cell Genet. 60 (2): 114–6. PMID 1611909. doi:10.1159/000133316. 
  3. Mancini A, Koch A, Wilms R, Tamura T (April 2002). "c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms". J. Biol. Chem. 277 (17): 14635–40. PMID 11847211. doi:10.1074/jbc.M109214200. 
  4. Courtneidge SA, Dhand R, Pilat D, Twamley GM, Waterfield MD, Roussel MF (March 1993). "Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor". EMBO J. 12 (3): 943–50. PMC 413295. PMID 7681396. 
  5. Mancini A, Niedenthal R, Joos H, Koch A, Trouliaris S, Niemann H, Tamura T (September 1997). "Identification of a second Grb2 binding site in the v-Fms tyrosine kinase". Oncogene 15 (13): 1565–72. PMID 9380408. doi:10.1038/sj.onc.1201518. 
  6. Bourette RP, De Sepulveda P, Arnaud S, Dubreuil P, Rottapel R, Mouchiroud G (June 2001). "Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal". J. Biol. Chem. 276 (25): 22133–9. PMID 11297560. doi:10.1074/jbc.M101878200. 

Literatura[uredi - уреди | uredi izvor]

Vanjske veze[uredi - уреди | uredi izvor]