Lavoltidin

Lavoltidin
(IUPAC) ime
	[1-metil-5-({3-[3-(piperidin-1-ilmetil)fenoksi]propil}amino)-1H-1,2,4-triazol-3-il]metanol
Klinički podaci
Identifikatori
CAS broj	76956-02-0
ATC kod	nije dodeljen
PubChem	55473
ChemSpider	50093
UNII	X16K5179V5
Hemijski podaci
Formula	C19H29N5O2
Mol. masa	359,47 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C19H29N5O2/c1-23-19(21-18(15-25)22-23)20-9-6-12-26-17-8-5-7-16(13-17)14-24-10-3-2-4-11-24/h5,7-8,13,25H,2-4,6,9-12,14-15H2,1H3,(H,20,21,22) ; Key: VTLNPNNUIJHJQB-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	Uncontrolled
Način primene	Oralno

Lavoltidin (INN, USAN; AH-23,844, lokstidin) je veoma potentan i selektivan antagonist H₂ receptora, koji je bio u razvoju za tretman gastroesofagealne refluksne bolesti, ali je razvoj prekinut zbog otkrića da on proizvodi gastrične karcinoidne tumore kod glodara.^[4]^[5]

Povezano

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Washington, Neena (1991). Antacids and anti-reflux agents. Boca Raton: CRC Press. ISBN 0-8493-5444-7.
↑ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8.

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