AMN082

AMN082
	N,N'-dibenzhidriletan-1,2-diamin dihidrohlorid
Identifikacija
CAS registarski broj	97075-46-2
PubChem	11698390
ChemSpider	9873115
Jmol-3D slike	Slika 1; Slika 2
SMILES
	C(NCCNC(c1ccccc1)c2ccccc2)(c3ccccc3)c4ccccc4.Cl.Cl Cl.Cl.N(CCNC(c1ccccc1)c2ccccc2)C(c3ccccc3)c4ccccc4
InChI
	InChI=1S/C28H28N2.2ClH/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;/h1-20,27-30H,21-22H2;2*1H ; Kod: YRQCDCNQANSUPB-UHFFFAOYSA-N
Svojstva
Molekulska formula	C28H30Cl2N2
Molarna masa	465,4572
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

AMN082 (N,N'-dibenzhidriletan-1,2-diamin dihidrohlorid) je selektivni alosterni agonist metabotropnog glutamatnog receptora 7 (mGluR7).^[4]^[5] On oponaša dejstvo glutamata. AMN082 je prvi selektivni mGluR7 agonist.

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Li X, Gardner EL, Xi ZX (March 2008). „The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats”. Neuropharmacology 54 (3): 542–51. DOI:10.1016/j.neuropharm.2007.11.005. PMC 2410088. PMID 18155073.
↑ Palucha A, Klak K, Branski P, van der Putten H, Flor PJ, Pilc A (November 2007). „Activation of the mGlu7 receptor elicits antidepressant-like effects in mice”. Psychopharmacology (Berl.) 194 (4): 555–62. DOI:10.1007/s00213-007-0856-2. PMID 17622518.

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