GPR177
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| edit |
| G protein-coupled receptor 177 | |||||||
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| Identifikatori | |||||||
| Simboli | GPR177; MRP; C1orf139; FLJ23091; MGC131760; MGC14878; WLS | ||||||
| Vanjski ID | MGI: 1915401 HomoloGene: 11779 GeneCards: GPR177 Gene | ||||||
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| Pregled RNK izražavanja | |||||||
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| podaci | |||||||
| Ortolozi | |||||||
| Vrsta | Čovek | Miš | |||||
| Entrez | 79971 | 68151 | |||||
| Ensembl | ENSG00000116729 | ENSMUSG00000028173 | |||||
| UniProt | Q5T9L3 | Q8CDZ6 | |||||
| RefSeq (mRNA) | NM_001002292 | NM_026582 | |||||
| RefSeq (protein) | NP_001002292 | NP_080858 | |||||
| Lokacija (UCSC) | Chr 1: 68.34 - 68.47 Mb | Chr 3: 159.78 - 159.87 Mb | |||||
| PubMed pretraga | [1] | [2] | |||||
G protein-spregnuti receptor 177 (GPR177), koji je poznat kao Wntless, je ljudski gen[1] koji kodira receptor za Wnt proteine u Wnt-sekretirajućim ćelijama.[2]
Za Wntless je nedavno bilo pokazano da je kargo za retromer kompleks[2]
Literatura[uredi | uredi kod]
- ↑ „Entrez Gene: GPR177 G protein-coupled receptor 177”.
- ↑ 2,0 2,1 Eaton S (January 2008). „Retromer retrieves wntless”. Dev. Cell. 14 (1): 4–6. DOI:10.1016/j.devcel.2007.12.014. PMID 18194646.
Dodatna literatura[uredi | uredi kod]
- Gregory SG, Barlow KF, McLay KE, et al. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature 441 (7091): 315–21. DOI:10.1038/nature04727. PMID 16710414.
- Bänziger C, Soldini D, Schütt C, et al. (2006). „Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.”. Cell 125 (3): 509–22. DOI:10.1016/j.cell.2006.02.049. PMID 16678095.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”. DNA Res. 12 (2): 117–26. DOI:10.1093/dnares/12.2.117. PMID 16303743.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Clark HF, Gurney AL, Abaya E, et al. (2003). „The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”. Genome Res. 13 (10): 2265–70. DOI:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Matsuda A, Suzuki Y, Honda G, et al. (2003). „Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.”. Oncogene 22 (21): 3307–18. DOI:10.1038/sj.onc.1206406. PMID 12761501.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.