Mefentermin

Izvor: Wikipedia
Mefentermin
(IUPAC) ime
N,2-dimetil-1-fenilpropan-2-amin
Klinički podaci
Identifikatori
CAS broj 100-92-5
ATC kod C01CA11
PubChem[1][2] 3677
DrugBank DB01365
ChemSpider[3] 3549
UNII TEZ91L71V4 YesY
KEGG[4] D08180 YesY
ChEMBL[5] CHEMBL1201234 YesY
Hemijski podaci
Formula C11H17N 
Mol. masa 163,259 g/mol
SMILES eMolekuli & PubHem
Sinonimi methyl(2-methyl-1-phenylpropan-2-yl)amine
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

Mefentermin je srčani stimulans. On se ranije koristio kao komponenta Wyamine nazalni dekongestivnih inhalatora, i kao stimulans u psihijatriji.

On se koristi za tretiranje hipotenzije.[6]

Reference[uredi - уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594.  edit
  6. WHITTINGTON RM (May 1963). "Mephentemine Sulphate as a Hypertensive Agent in General Practice". J Coll Gen Pract 6 (2): 336–7. PMC 1878111. PMID 14000433. 

Spoljašnje veze[uredi - уреди]