Metipranolol
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| |||
| (IUPAC) ime | |||
|---|---|---|---|
| (RS)-4[-2-hidroksi-3-(izopropilamino)propil]oksi2,3,6-trimetilfenil acetat | |||
| Klinički podaci | |||
| Robne marke | Optipranolol | ||
| AHFS/Drugs.com | Mikromedeks, detaljne potrošačke informacije | ||
| MedlinePlus | a601078 | ||
| Identifikatori | |||
| CAS broj | 22664-55-7 | ||
| ATC kod | S01ED04 C07BA68 | ||
| PubChem[1][2] | 31477 | ||
| DrugBank | DB01214 | ||
| ChemSpider[3] | 29193 | ||
| UNII | X39AL81KEB 
| ||
| KEGG[4] | D02374
| ||
| ChEMBL[5] | CHEMBL1291
| ||
| Hemijski podaci | |||
| Formula | C17H27NO4 | ||
| Mol. masa | 309,401 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Metipranolol (OptiPranolol, Betanol, Disorat, Trimepranol) je neselektivni beta blokator koji se koristi u obliku kapi za oči za tretiranje glaukoma. On se brzo metaboliše u desacetilmetipranolol.[6]
Reference[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Maffei Facino, R.; Bertuletti, R.; Carini, M.; Tofanetti, O. (1980). „In vitro metabolism of methypranolol by rat liver”. Analytical Chemistry Symposia Series 4 (6): 217–223.
