Iproniazid

Iproniazid
(IUPAC) ime
	N'-izopropilizonikotinohidrazid
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	54-92-2
ATC kod	N06AF05
PubChem	3748
DrugBank	DB04818
ChemSpider	3617
UNII	D892HFI3XA
KEGG	D02579
ChEMBL	CHEMBL92401
Hemijski podaci
Formula	C9H13N3O
Mol. masa	179,219
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C9H13N3O/c1-7(2)11-12-9(13)8-3-5-10-6-4-8/h3-7,11H,1-2H3,(H,12,13) ; Key: NYMGNSNKLVNMIA-UHFFFAOYSA-N
Farmakokinetički podaci
Bioraspoloživost	?
Metabolizam	?
Poluvreme eliminacije	?
Izlučivanje	?
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	?
Način primene	?

Iproniazid (Eufozid, Iprazid, Ipronid, Ipronin, Marsilid, Rivivol) je hidrazinski lek koji je korišten kao antidepresiv.^[6] On deluje kao ireverzibilni i neselektivni inhibitor monoaminske oksidaze (MAOI).^[7]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Robert A. Maxwell, Shohreh B. Eckhardt (1990). Drug discovery. Humana Press. str. 143–154. ISBN 9780896031807.
↑ Fagervall I, Ross SB (April 1986). „Inhibition of monoamine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors”. Biochemical pharmacology 35 (8): 1381–7. DOI:10.1016/0006-2952(86)90285-6. PMID 2870717.

Vidi još[uredi | uredi kod]

Hidrazin (antidepresiv)

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[bookDrug_discovery-6] Robert A. Maxwell, Shohreh B. Eckhardt (1990). Drug discovery. Humana Press. str. 143–154. ISBN 9780896031807.

[pmid2870717-7] Fagervall I, Ross SB (April 1986). „Inhibition of monoamine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors”. Biochemical pharmacology 35 (8): 1381–7. DOI:10.1016/0006-2952(86)90285-6. PMID 2870717.

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Iproniazid

Reference[uredi | uredi kod]

Vidi još[uredi | uredi kod]

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