Izoetarin
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| |||
| (IUPAC) ime | |||
|---|---|---|---|
| 4- {1-hidroksi-2-[(propan-2-il)amino]butil}benzen-1,2-diol | |||
| Klinički podaci | |||
| Robne marke | Beta-2, Bronkometer, Bronkosol, Dey-Lute Isoetharine | ||
| AHFS/Drugs.com | Monografija | ||
| Identifikatori | |||
| CAS broj | 530-08-5 | ||
| ATC kod | R03AC07 , R03CC06 | ||
| PubChem[1][2] | 3762 | ||
| DrugBank | DB00221 | ||
| ChemSpider[3] | 3630 | ||
| KEGG[4] | C07053 
| ||
| Hemijski podaci | |||
| Formula | C13H21NO3 | ||
| Mol. masa | 239.3107 | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
| Način primene | inhalacija | ||
Izoetarin je selektivni agonist Beta-2 adrenergičkog receptora koji se koristi kao brzo delujući bronhodilatator za tretman hronične opstruktivne bolesti pluća, bronhitisa i astme.[5][6][7]
Reference[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Emerman CL, Cydulka RK, Effron D, Lukens TW, Gershman H, Boehm SP: A randomized, controlled comparison of isoetharine and albuterol in the treatment of acute asthma. Ann Emerg Med. 1991 Oct;20(10):1090-3. PMID 1928879
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682.
- ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412.
