Monokin

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Monokin je tip citokina koji prvenstveno nastaje u monocitima i makrofagama.[1] Primeri monokina su interleukin 1 i faktor nekroze tumora-alfa.

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Monokini koje ozlučuju makrofage mogu da privuku neutrofile putem procesa hemotakse.[2][3]

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Reference[uredi - уреди | uredi izvor]

  1. H.Dieter Welscher, Nicole Montandona and André Cruchaud. "Effects of macrophage culture supernatants (monokines) on phagocytosis, catabolism, lysosomal enzymes and cyclic amp of isologous macrophages". Immunology Letters 2 (1): 15-22. DOI:10.1016/0165-2478(80)90067-X. http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T75-476MWVS-77&_user=557717&_coverDate=08%2F31%2F1980&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1412001540&_rerunOrigin=google&_acct=C000028418&_version=1&_urlVersion=0&_userid=557717&md5=f505ef11aab6fafbe5a0866a61025cee. 
  2. Clouse KA, Powell D, Washington I, Poli G, Strebel K, Farrar W, Barstad P, Kovacs J, Fauci AS, Folks TM. (1989). "Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone". J Immunol 142 (2): 431-8. PMID 2463307. 
  3. Ho WZ, Tomassini N, Cherukuri R, Shun-D G, Song L, Lee HR, Douglas SD. "Monokine-mediated increase in human immunodeficiency virus type 1 expression in chronically infected promonocyte- and T-cell-derived lines". Clin Diagn Lab Immunol 1 (5): 517-25. PMID 8556495. 

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