Curcumin
IUPAC ime
(1E ,6E )-1,7-Bis(4-hidroksi-3-metoksifenil)-1,6-heptadien-3,5-dion
Drugi nazivi
Diferuloilmetan; C.I. 75300
Identifikacija
CAS registarski broj
458-37-7 Y
PubChem [1] [2] 969516
ChemSpider [3] 839564 Y
UNII
IT942ZTH98 Y
ChEBI
3962
ChEMBL [4] CHEMBL116438 Y
Jmol -3D slike
Slika 1
O=C(\C=C\c1ccc(O)c(OC)c1)CC(=O)\C=C\c2cc(OC)c(O)cc2
InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ Y Y
InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
Svojstva
Molekulska formula
C21 H20 O6
Molarna masa
368.38 g mol−1
Agregatno stanje
Svetlo žuto-narandžasti prah
Tačka topljenja
183 °C, 456 K, 361 °F
Y (šta je ovo?)
(verifikuj)
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
Infobox references
Kurkumin je glavni predstavnik kurkuminoida iz popularnog indijskog začina kurkuma , koji je član đumbir porodice (Zingiberaceae desmetoksikurkumin i bis-desmetoksikurkumin . Kurkuminoidi su prirodni fenoli koji daju žutu boju kurkuma začinu. Kurkumin ima nekoliko tautomernih formi, uključujući 1,3-diketo formu i dve enolne forme. Enolna forma je energetski stabilnija u čvrstoj fazi i u rastvoru.[5]
Kurkumin ima svetlo žutu boju i može se koristiti za bojenje hrane . On je prehrambeni aditivi sa E brojem E100.[6]
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.” . Drug Discov Today 15 (23-24): 1052-7. DOI :10.1016/j.drudis.2010.10.003 . PMID 20970519 . http://www.sciencedirect.com/science/article/pii/S1359644610007737 . edit ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4 : 217-241. DOI :10.1016/S1574-1400(08)00012-1 . ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining” . J Cheminform 2 (1): 3. DOI :10.1186/1758-2946-2-3 . PMID 20331846 . http://www.jcheminf.com/content/2/1/3 . edit ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI :10.1093/nar/gkr777 . PMID 21948594 . edit ↑ Kolev, Tsonko M.; Velcheva, Evelina A.; Stamboliyska, Bistra A.; Spiteller, Michael (2005). „DFT and experimental studies of the structure and vibrational spectra of curcumin”. International Journal of Quantum Chemistry 102 (6): 1069–79. DOI :10.1002/qua.20469 . ↑ Food Standards Australia New Zealand. „Food Additives- Numerical List” . Arhivirano iz originala 2009-06-25. https://web.archive.org/web/20090625024756/http://www.foodstandards.gov.au/newsroom/publications/choosingtherightstuff/foodadditivesnumeric1680.cfm . Pristupljeno 2. 12. 2009 .
Esatbeyoglu, Tuba; Huebbe, Patricia; Ernst, Insa M. A.; Chin, Dawn; Wagner, Anika E.; Rimbach, Gerald (2012). „Curcumin-From Molecule to Biological Function”. Angewandte Chemie International Edition 51 (22): 5308. DOI :10.1002/anie.201107724 .
