Heptadekanska kiselina

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Heptadekanska kiselina
Heptadecanoic acid.png
IUPAC ime
Drugi nazivi Margarinska kiselina
n-margarinska kiselina
n-Heptadekanska kiselina
Identifikacija
CAS registarski broj 506-12-7 YesY
ChemSpider[1] 10033 YesY
MeSH Heptadecanoic+acid
ChEBI 32365
ChEMBL[2] CHEMBL1172910 YesY
Jmol-3D slike Slika 1
Svojstva
Molekulska formula C17H34O2
Molarna masa 270.45 g/mol
Agregatno stanje beli kristali
Gustina 0.853 g/cm3
Tačka topljenja

61 °C

Tačka ključanja

227 °C (100 mm Hg)

Rastvorljivost u vodi nerastvorljiva
Srodna jedinjenja
Srodna višemasne kiseline Palmitinska kiselina
Stearinska kiselina
Сродна једињења Heptadekanol
Heptadekanal



Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

Heptadekanska kiselina ili margarinska kiselina je zasićena masna kiselina.

Njena formula je CH3(CH2)15COOH. Javlja se u masti i mlečnoj masti preživara.[3][4][5][6] Soli i estri heptadekanske kiseline se zovu heptadekanoati.

Osobine[uredi - уреди | uredi izvor]

Osobina Vrednost
Particioni koeficijent[7] (ALogP) 6,8
Rastvorljivost[8] (logS, log(mol/L)) -7,2
Polarna površina[9] (PSA, Å2) 37,3

Reference[uredi - уреди | uredi izvor]

  1. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  2. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  3. R. P. HANSEN, F. B. SHORLAND & N. JUNE COOKE (1957). "Occurrence in Butterfat of n-Heptadecanoic Acid (Margaric Acid)". Nature 179 (98). doi:10.1038/179098a0. 
  4. Lide David R., ur. (2006). CRC Handbook of Chemistry and Physics (87th izd.). Boca Raton, FL: CRC Press. 0-8493-0487-3. http://www.hbcpnetbase.com. 
  5. Susan Budavari, ur. (2001). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (13th izd.). Merck Publishing. ISBN 0-911910-13-1. http://www.merckbooks.com/mindex/online.html. 
  6. "Human Metabolome Database, HMDB02259". http://www.hmdb.ca/metabolites/HMDB02259. pristupljeno 8. 11. 2008.. 
  7. Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods". J. Phys. Chem. A 102: 3762–3772. doi:10.1021/jp980230o. 
  8. Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). "Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices". Chem Inf. Comput. Sci. 41: 1488–1493. PMID 11749573. doi:10.1021/ci000392t. 
  9. Ertl P., Rohde B., Selzer P. (2000). "Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties". J. Med. Chem. 43: 3714–3717. PMID 11020286. doi:10.1021/jm000942e. 

Literatura[uredi - уреди | uredi izvor]

Spoljašnje veze[uredi - уреди | uredi izvor]