Lipoksin

Lipoksin B4
	5S,14R,15S-Trididroks-6E,8Z,10E,12E -eikozatetraenoinska kiselina
Drugi nazivi	LXB4
Identifikacija
CAS registarski broj	92950-25-9
PubChem	5280915
ChemSpider	4444430
ChEBI	6499
Jmol-3D slike	Slika 1
SMILES
	O=C(O)CCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCCC
InChI
	InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1 ; Kod: UXVRTOKOJOMENI-WLPVFMORSA-N InChI=1/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1; Kod: UXVRTOKOJOMENI-WLPVFMORBP
Svojstva
Molekulska formula	C20H32O5
Molarna masa	352,46508 g/mol
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Lipoksini su bioaktivni proizvodi izvedeni iz arahidonske kiseline.^[4] Oni ispoljavaju brojne proinflamatarne i antiinflamatorne efekte. Lipoksini su kratkotrajni endogeni neklasični eikozanoidi čija pojava je indikacija zapaljenja. Oni se obeležavaju sa LX, što je akronim za interakcione proizvode lipoksigenaze.

Poznata su dva lipoksina: lipoksin A₄ (LXA₄) i lipoksin B₄ (LXB₄). Još jedna analogna klasa, epilipoksini, se formira putem neenzimatske peroksidacije.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Charles N. Serhan, Mats Hamberg, and Bengt Samuelsson (1. 9. 1984.). „Lipoxins: Novel Series of Biologically Active Compounds Formed from Arachidonic Acid in Human Leukocytes” (pdf). Pristupljeno 2. 2. 2006. Original description of lipoxins

Spoljašnje veze

Portal Hemija

MeSH Lipoxins

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[Serhan-4] Charles N. Serhan, Mats Hamberg, and Bengt Samuelsson (1. 9. 1984.). „Lipoxins: Novel Series of Biologically Active Compounds Formed from Arachidonic Acid in Human Leukocytes” (pdf). Pristupljeno 2. 2. 2006. Original description of lipoxins

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