7-Hlorokinurenska kiselina

7-Hlorokinurenska kiselina
	7-hloro-4-hidroksi-2-hinolinkarboksilna kiselina
Drugi nazivi	7-CTKA
Identifikacija
ChemSpider	1813
Jmol-3D slike	Slika 1
SMILES
	C1=CC2=C(C=C1Cl)N=C(C=C2O)C(=O)O
InChI
	InChI=1S/C10H6ClNO3/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13/h1-4H,(H,12,13)(H,14,15); Kod: UAWVRVFHMOSAPU-UHFFFAOYSA-N
Svojstva
Molekulska formula	C10H6ClNO3
Molarna masa	223.61 g mol−1
	; ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

7-Hlorokinurenska kiselina (7-CTKA) je antagonist NMDA receptora sa antidepresantskim dejstvom na pacovima.^[2]^[3]

Reference[uredi | uredi kod]

↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Kemp, JA; Foster, AC; Leeson, PD; Priestley, T; Tridgett, R; Iversen, LL; Woodruff, GN (1988). „7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex”. Proceedings of the National Academy of Sciences of the United States of America 85 (17): 6547–6550. DOI:10.1073/pnas.85.17.6547. PMC 282010.
↑ Zhu, WL; Wang, SJ; Liu, MM; Shi, HS; Zhang, RX; Liu, JF; Ding, ZB; Lu, L (2013). „Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats”. Journal of psychiatry & neuroscience : JPN 38 (5): 306–16. DOI:10.1503/jpn.120228. PMC 3756114. PMID 23611177.