7-Hlorokinurenska kiselina

Izvor: Wikipedia
7-Hlorokinurenska kiselina
7-Chlorokynurenate.png
IUPAC ime
Drugi nazivi 7-CTKA
Identifikacija
ChemSpider[1] 1813
Jmol-3D slike Slika 1
Svojstva
Molekulska formula C10H6ClNO3
Molarna masa 223.61 g mol−1



Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

7-Hlorokinurenska kiselina (7-CTKA) je antagonist NMDA receptora sa antidepresantskim dejstvom na pacovima.[2][3]

Reference[uredi - уреди]

  1. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  2. Kemp, JA; Foster, AC; Leeson, PD; Priestley, T; Tridgett, R; Iversen, LL; Woodruff, GN (1988). "7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex". Proceedings of the National Academy of Sciences of the United States of America 85 (17): 6547–6550. doi:10.1073/pnas.85.17.6547. PMC 282010. 
  3. Zhu, WL; Wang, SJ; Liu, MM; Shi, HS; Zhang, RX; Liu, JF; Ding, ZB; Lu, L (2013). "Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats". Journal of psychiatry & neuroscience : JPN 38 (5): 306–16. doi:10.1503/jpn.120228. PMC 3756114. PMID 23611177.