UDP-N-acetilmuramat-L-alaninska ligaza
| UDP-N-acetilmuramat-L-alaninska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.8 | ||||||||
| CAS broj | 9023-52-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
UDP-N-acetilmuramat-L-alaninska ligaza (EC 6.3.2.8, MurC sintetaza, UDP-N-acetilmuramoil-L-alanin sintetaza, uridin difosfo-N-acetilmuramoilalanin sintetaza, UDP-N-acetilmuramoilalanin sintetaza, enzim dodavanja L-alanina, UDP-acetilmuramil-L-alanin sintetaza, UDPMurNAc-L-alanin sintetaza, L-Ala ligaza, uridin difosfat N-acetilmuramat:L-alanin ligaza, uridin 5'-difosfat-N-acetilmuramil-L-alanin sintetaza, uridin-difosfat-N-acetilmuramat:L-alanin ligaza, UDP-MurNAc:L-alanin ligaza, enzim dodavanja alanina, UDP-N-acetilmuramil:L-alanin ligaza) je enzim sa sistematskim imenom UDP-N-acetilmuramat:L-alanin ligaza (formira ADP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.
- ↑ Ito, E. and Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. I. Enzymatic addition of L-alanine, D-glutamic acid, and L-lysine”. J. Biol. Chem. 237: 2689-2695.
- ↑ Nathenson, S.G., Strominger, J.L. and Ito, E. (1964). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. IV. Purification and properties of D-glutamic acid-adding enzyme”. J. Biol. Chem. 239: 1773-1776. PMID 14213349.
- ↑ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503-519. PMID 11699883.
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
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