Saharoza sintaza

Iz Wikipedije, slobodne enciklopedije
Idi na navigaciju Idi na pretragu
Saharoza sintaza
3s29.jpg
Identifikatori
EC broj 2.4.1.13
CAS broj 2604301
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Saharoza sintaza (EC 2.4.1.13, UDPglukoza-fruktoza glukoziltransferaza, saharozna sintetaza, saharoza-UDP glukoziltransferaza, saharoza-uridin difosfatna glukoziltransferaza, uridin difosfoglukoza-fruktozna glukoziltransferaza) je enzim sa sistematskim imenom NDP-glukoza:D-fruktoza 2-alfa-D-glukoziltransferaza.[1][2][3][4][5][6][7][8][9][10] Ovaj enzim katalizuje sledeću hemijsku reakciju

NDP-glukoza + D-fruktoza NDP + saharoza

Mada se UDP generalno smatra preferentnim nukleozid difosfatom za sintezu saharoze, brojne studije su pokazale da ADP isto tako može da bude efektivan akceptor.

Reference[uredi - уреди | uredi izvor]

  1. Avigad, G. and Milner, Y. (1966). "UDP-glucose:fructose transglucosylase from sugar beet roots". Methods Enzymol. 8: 341–345. 
  2. Cardini, C.E., Leloir, L.F. and Chiriboga, J. (1955). "The biosynthesis of sucrose". J. Biol. Chem. 214: 149–155. PMID 14367373. 
  3. Delmer, D.P. (1972). "The purification and properties of sucrose synthetase from etiolated Phaseolus aureus' seedlings". J. Biol. Chem. 247: 3822–3828. PMID 4624446. 
  4. Murata, T., Sugiyama, T., Minamikawa, T. and Akazawa, T. (1966). "Enzymic mechanism of starch synthesis in ripening rice grains. Mechanism of the sucrose-starch conversion". Arch. Biochem. Biophys. 113: 34–44. PMID 5941994. 
  5. Nakai, T., Konishi, T., Zhang, X.-Q., Chollet, R., Tonouchi, N., Tsuchida, T., Yoshinaga, F., Mori, H., Sakai, F. and Hayashi, T. (1998). "An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11". Plant Cell Physiol. 39: 1337–1341. PMID 10050318. 
  6. Porchia, A.C., Curatti, L. and Salerno, G.L. (1999). "Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence". Planta 210: 34–40. PMID 10592030. 
  7. Ross, H.A. and Davies, H.V. (1992). "Purification and characterization of sucrose synthase from the cotyledons of Vicia fava L". Plant Physiol. 100: 1008–1013. PMID 16653008. 
  8. Silvius, J.E. and Snyder, F.W. (1979). "Comparative enzymic studies of sucrose metabolism in the taproots and fibrous roots of Beta vulgaris L". Plant Physiol. 64: 1070–1073. PMID 16661094. 
  9. Tanase, K. and Yamaki, S. (2000). "Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit". Plant Cell Physiol. 41: 408–414. PMID 10845453. 
  10. Baroja-Fernández, E., Muñnoz, F.J., Saikusa, T., Rodríguez-López, M., Akazawa, T. and Pozueta-Romero, J. (2003). "Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants". Plant Cell Physiol. 44: 500–509. PMID 12773636. 

Literatura[uredi - уреди | uredi izvor]

Spoljašnje veze[uredi - уреди | uredi izvor]