N-acetilneuraminat 4-O-acetiltransferaza
Izgled
N-acetilneuraminat 4-O-acetiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.3.1.44 | ||||||||
CAS broj | 51004-25-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilneuraminat 4-O-acetiltransferaza (EC 2.3.1.44, sijalatna O-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:N-acetilneuraminat 4-O-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + N-acetilneuraminat KoA + N-acetil-4-O-acetilneuraminat
Slobodni i glikozidno vezani N-acetil- i N-glikolil- neuraminati mogu da deluju kao O-acetil akceptori.
- ↑ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. I. Inkorporation von [14C]Acetate in Schnitte der Unterkieferspeicheldrüse von Rind und Pferd”. Hoppe-Seyler's Z. Physiol. Chem. 351: 595-602. PMID 5446640.
- ↑ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. II. Untersuchungen über Substrat und intracelluläre Lokalisation der Acetyl-coenzym A: N-acetylneuraminat-7- and 8-O-acetyltransferase von Rind”. Hoppe-Seyler's Z. Physiol. Chem. 351: 749-758. PMID 5425947.
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