Leucin-tRNK ligaza
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| Leucin-tRNK ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.1.1.4 | ||||||||
| CAS broj | 9031-15-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Leucin-tRNK ligaza (EC 6.1.1.4, leucil-tRNK sintetaza, leucil-transferna ribonukleatna sintetaza, leucil-transferna RNK sintetaza, leucil-transferna ribonukleinsko kiselinska sintetaza, leucin-tRNK sintetaza, leucinska translaza) je enzim sa sistematskim imenom L-leucin:tRNKLeu ligaza (formira AMP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Reference[uredi | uredi kod]
- ↑ Allen, E.H., Glassman, E. and Schweet, R.S. (1960). „Incorporation of amino acids into ribonucleic acid. I. The role of activating enzymes”. J. Biol. Chem. 235: 1061-1067. PMID 13792726.
- ↑ Berg, P., Bergmann, F.H., Ofengand, E.J. and Dieckmann, M. (1961). „The enzymic synthesis of amino acyl derivatives of ribonucleic acid. I. The mechanism of leucyl-, valyl-, isoleucyl- and methionyl ribonucleic acid formation”. J. Biol. Chem. 236: 1726-1734.
- ↑ Bergmann, F.H., Berg, P. and Dieckmann, M. (1961). „The enzymic synthesis of amino acyl derivatives of ribonucleic acid. II. The preparation of leucyl-, valyl-, isoleucyl- and methionyl ribonucleic acid synthetases from Escherichia coli”. J. Biol. Chem. 236: 1735-1740.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.