Karnitin O-oktanoiltransferaza
| Karnitin O-oktanoiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.137 | ||||||||
| CAS broj | 39369-19-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Karnitin O-oktanoiltransferaza (EC 2.3.1.137, srednjelančana/dugolančana karnitin aciltransferaza, karnitin srednjelančana aciltransferaza, lako rastvorna mitohondrijska karnitinska palmitoiltransferaza) je enzim sa sistematskim imenom oktanoil-KoA:L-karnitin O-oktanoiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- oktanoil-KoA + L-karnitin KoA + L-oktanoilkarnitin
Ovaj enzim deluje na opseg acil-KoA molekula, sa optimalnom aktivnošću na C6 ili C8 acil grupama, cf. EC 2.3.1.7 (karnitin O-acetiltransferaza) i EC 2.3.1.21 (karnitin O-palmitoiltransferaza).
- ↑ Farrell, S.O., Fiol, C.J., Reddy, J.K. and Bieber, L.L. (1984). „Properties of purified carnitine acyltransferases of mouse liver peroxisomes”. J. Biol. Chem. 259: 13089-13095. PMID 6436243.
- ↑ Healy, M.J., Kerner, J. and Bieber, L.L. (1988). „Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?”. Biochem. J. 249: 231-237. PMID 3342008.
- ↑ Miyazawa, S., Ozasa, H., Osumi, T. and Hashimoto, T. (1983). „Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver”. J. Biochem. (Tokyo) 94: 529-542. PMID 6630173.
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