Karboksipeptidaza B

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Karboksipeptidaza B
Identifikatori
EC broj 3.4.17.2
CAS broj 9025-24-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Karboksipeptidaza B (EC 3.4.17.2, protaminaza, pankreasna karboksipeptidaza B, tkivna karboksipeptidaza B, peptidil-L-lizin (L-arginin) hidrolaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Preferentno odvajanje C-terminalne aminokiseline lizina ili arginina.

Ovaj cinkov enzim se formira iz prokarboksipeptidaze B.

Reference[uredi | uredi kod]

  1. Folk, J.E. (1970). „Carboxypeptidase B (porcine pancreas)”. Methods Enzymol. 19: 504-508. 
  2. Brodrick, J.W., Geokas, M.C. and Largman, C. (1976). „Human carboxypeptidase B. II. Purification of the enzyme from pancreatic tissue and comparison with the enzymes present in pancreatic secretion”. Biochim. Biophys. Acta 452: 468-481. PMID 1009123. 
  3. Butterworth, J. and Duncan, J.J. (1979). „Carboxypeptidase B activity of cultured skin fibroblasts and relationship to cystic fibrosis”. Clin. Chim. Acta 97: 39-43. PMID 40714. 
  4. Wallace, E.F., Evans, C.J., Jurik, S.M., Mefford, I.N. and Barchas, J.D. (1982). „Carboxypeptidase B activity from adrenal medulla. Is it involved in the processing of proenkephalin?”. Life Sci. 31: 1793-1796. PMID 6130442. 

Literatura[uredi | uredi kod]

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