Vanilinska sintaza
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| Vanilinska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.2.41 | ||||||||
| CAS broj | 449168-60-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Vanilinska sintaza (EC 4.1.2.41, 3-hidroksi-3-(4-hidroksi-3-metoksifenil)propionil-KoA:vanilin lijaza (formira acetil-KoA)) je enzim sa sistematskim imenom 3-hidroksi-3-(4-hidroksi-3-metoksifenil)propanoil-KoA vanilin-lijaza (formira acetil-KoA).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3-hidroksi-3-(4-hidroksi-3-metoksifenil)propanoil-KoA vanilin + acetil-KoA
Ovaj enzim učestvuje zajedno sa EC 4.2.1.101, trans-feruloil-KoA hidratazom, u produkciji vanilina iz trans-ferulinske kiselina.
Reference[uredi | uredi kod]
- ↑ Narbad, A. and Gasson, M.J. (1998). „Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens”. Microbiology 144: 1397-1405. PMID 9611814.
- ↑ Pometto, A.L. and Crawford, D.L. (1983). „Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus”. Appl. Environ. Microbiol. 45: 1582-1585. PMID 6870241.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.