UDP-N-acetilmuramoilalanin-D-glutamatska ligaza
(Preusmjereno sa stranice UDP-Mur-NAC-L-Ala:D-Glu ligase)
| UDP-N-acetilmuramoilalanin-D-glutamatska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.9 | ||||||||
| CAS broj | 9023-59-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
UDP-N-acetilmuramoilalanin-D-glutamatska ligaza (EC 6.3.2.9, MurD sintetaza, UDP-N-acetilmuramoil-L-alanil-D-glutamat sintetaza, uridin difosfo-N-acetilmuramoilalanil-D-glutamat sintetaza, enzim dodavanja D-glutamata, D-glutamatna ligaza, UDP-Mur-NAC-L-Ala:D-Glu ligaza, UDP-N-acetilmuramoil-L-alanin:glutamat ligaza (formira ADP), UDP-N-acetilmuramoilalanin—D-glutamat ligaza) je enzim sa sistematskim imenom UDP-N-acetilmuramoil-L-alanin:D-glutamat ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + UDP-N-acetilmuramoil-L-alanin + D-glutamat ADP + fosfat + UDP-N-acetilmuramoil-L-alanil-D-glutamat
Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.
- ↑ Ito, E. and Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. I. Enzymatic addition of L-alanine, D-glutamic acid, and L-lysine”. J. Biol. Chem. 237: 2689-2695.
- ↑ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503-519. PMID 11699883.
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
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