Triptofan transaminaza
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| Triptofan transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.6.1.27 | ||||||||
| CAS broj | 9022-98-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Triptofan transaminaza (EC 2.6.1.27, L-fenilalanin-2-oksoglutaratna aminotransferaza, triptofanska aminotransferaza, 5-hidroksitriptofan-ketoglutarinska transaminaza, hidroksitriptofanska aminotransferaza, L-triptofanska aminotransferaza, L-triptofanska transaminaza) je enzim sa sistematskim imenom L-triptofan:2-oksoglutarat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Oksaloacetat može da zameni 2-oksoglutarat. On takođe deluje na 5-hidroksitriptofan i u manjoj meri na fenilne aminokiseline.
Reference[uredi | uredi kod]
- ↑ George, H. and Gabay, S. (1968). „Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase”. Biochim. Biophys. Acta 167: 555-566. PMID 5722279.
- ↑ O'Neil, S.R. and DeMoss, R.D. (1968). „Tryptophan transaminase from Clostridium sporogenes”. Arch. Biochem. Biophys. 127: 361-368. PMID 5697992.
- ↑ Tangen, O., Fonnum, F. and Haavaldsen, R. (1965). „Separation and purification of aromatic amino acid transaminases from rat brain”. Biochim. Biophys. Acta 96: 82-90. PMID 14285270.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.