Triptofan 2-monooksigenaza
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| Triptofan 2-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.12.3 | ||||||||
| CAS broj | 37256-65-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Triptofan 2-monooksigenaza (EC 1.13.12.3, triptofanska 2-monooksigenaza) je enzim sa sistematskim imenom L-triptofan:kiseonik 2-oksidoreduktaza (dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-triptofan + O2 (indol-3-il)acetamid + CO2 + H2O
Reference[uredi | uredi kod]
- ↑ Kosuge, T., Heskett, M.G. and Wilson, E.E. (1966). „Microbial synthesis and degradation of indole-3-acetic acid. I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi”. J. Biol. Chem. 241: 3738-3744. PMID 5916389.
- ↑ Kuo, T.T. and Kosuge, T. (1969). „Factors influencing the production and further metabolism of indole-3-acetic acid by Pseudomonas savastanoi”. J. Gen. Appl. Microbiol. 15: 51-63.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.